Isolation and Evaluation of Antibacterial Potential Test of Plant Carthamus oxycantha

  • Amir Hassan Department of Chemistry, Government Post Graduate College Mardan, Abdul Wali Khan University, Mardan 23200 Khyber Pakhtunkhwa, Pakistan
  • Ibad Ullah Department of Botany, Government Post Graduate College Mardan, Abdul Wali Khan University, Mardan 23200 Khyber Pakhtunkhwa, Pakistan
  • Waqas Ahmad Department of Botany, Government Post Graduate College Mardan, Abdul Wali Khan University, Mardan 23200 Khyber Pakhtunkhwa, Pakistan
Keywords: Carthamus oxycantha, Isolation, Antibacterial, Agar well diffusion, E-coli, S. aureus

Abstract

The present investigation was initiated to find a suitable alternative to synthetic antibiotics for the management of diseases caused by bacteria. Carthamus oxycantha.L locally known as wild safflower member of family Asteraceae that grows wildly. The study was conducted using as Agar well diffusion to trace the antibacterial potential for to evaluate the efficiency of ethanolic extract of Carthamus oxycantha with concentration of 05, 10, 15, and 20 mg/ml against gram-positive Staphylococcus aureus and gram-negative Escherichia Coli species and them compared with that of Clindamycin, Ampicillin and Kanamycin (10 mg). Zone of inhibition for the extracts were 10.667 to 20.00 mm as compared to standard drug Clindamycin, Ampicillin and kanamycin (15.00-20.00 mm). Antibacterial assays indicates that Carthamus oxycantha has potential natural antimicrobial agents against E-coli and S. aureus. The findings of the present study suggested that ethanolic extract of C. oxycantha has strong potential to serve as possible antibacterial.

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Author Biographies

Amir Hassan, Department of Chemistry, Government Post Graduate College Mardan, Abdul Wali Khan University, Mardan 23200 Khyber Pakhtunkhwa, Pakistan

Department of Chemistry, Government Post Graduate College Mardan, Abdul Wali Khan University, Mardan 23200  Khyber Pakhtunkhwa, Pakistan

Ibad Ullah, Department of Botany, Government Post Graduate College Mardan, Abdul Wali Khan University, Mardan 23200 Khyber Pakhtunkhwa, Pakistan

Department of Botany, Government Post Graduate College Mardan, Abdul Wali Khan University, Mardan 23200      Khyber Pakhtunkhwa, Pakistan

Waqas Ahmad , Department of Botany, Government Post Graduate College Mardan, Abdul Wali Khan University, Mardan 23200 Khyber Pakhtunkhwa, Pakistan

Department of Botany, Government Post Graduate College Mardan, Abdul Wali Khan University, Mardan 23200 Khyber Pakhtunkhwa, Pakistan

References

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Published
2021-09-09
How to Cite
Hassan, A., Ullah, I., & Ahmad , W. (2021). Isolation and Evaluation of Antibacterial Potential Test of Plant Carthamus oxycantha. Journal of Tropical Pharmacy and Chemistry, 5(4), 299-308. Retrieved from https://jtpc.farmasi.unmul.ac.id/index.php/jtpc/article/view/343